Archived Comments for:
Methylation of cancer related genes in tumor and peripheral blood DNA from the same breast cancer patient as two independent events
Tomasz K Wojdacz, Department of Human GeneticsWilhelm Meyers Alle 4 Denmark
3 January 2013
In the paper we wrote:
"The study by Wong et al. [2] involved 12 breast cancer patients paired tumor and PB DNA samples. The authors in this study reported generally low levels of methylation detected in PB (for most of the samples less than 5%) and furthermore, three patients with BRCA1 methylation in PB DNA did not display BRCA1 methylation in the paired tumor sample."
The correct version of this sentence should read:
"The study by Wong et al. [2] involved 9 breast cancer patients with tumor and paired PB DNA samples displaying methylation of the BRCA1 gene. The authors in this study reported generally low levels of methylation detected in PB (for most of the samples less than 5%) and furthermore, one patient with BRCA1 methylation in PB DNA did not display BRCA1 methylation in the paired tumor sample and for one patient the methylation in tumor DNA could not be confirmed by secondary method used in the experiment."
We sincerely apologize the authors of the quoted paper for the mistake
Author's correction
3 January 2013
In the paper we wrote:
"The study by Wong et al. [2] involved 12 breast cancer patients paired tumor and PB DNA samples. The authors in this study reported generally low levels of methylation detected in PB (for most of the samples less than 5%) and furthermore, three patients with BRCA1 methylation in PB DNA did not display BRCA1 methylation in the paired tumor sample."
The correct version of this sentence should read:
"The study by Wong et al. [2] involved 9 breast cancer patients with tumor and paired PB DNA samples displaying methylation of the BRCA1 gene. The authors in this study reported generally low levels of methylation detected in PB (for most of the samples less than 5%) and furthermore, one patient with BRCA1 methylation in PB DNA did not display BRCA1 methylation in the paired tumor sample and for one patient the methylation in tumor DNA could not be confirmed by secondary method used in the experiment."
We sincerely apologize the authors of the quoted paper for the mistake
The Authors
Competing interests
We have no competing interests