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  1. Case Report

    Malignant gastrointestinal neuroectodermal tumor: a case report and review of the literature

    Malignant gastrointestinal neuroectodermal tumor (GNET) is an extremely rare entity that was first described by Zambrano et al. in 2003 as “Clear cell sarcoma-like tumor of the gastrointestinal tract”. It shar...

    Mohammed J. Alyousef, Jumana A. Alratroot, Tarek ElSharkawy, Mohamed A. Shawarby, Mohammad A. Al hamad, Tarek M. Hashem and Ahmed Alsayyah

    Diagnostic Pathology 2017 12:29

    Published on: 20 March 2017

  2. Case Report

    Cerebellar ependymoma with overlapping features of clear-cell and tanycytic variants mimicking hemangioblastoma: a case report and literature review

    Imaging and histology of clear-cell ependymoma and cerebellum-based hemangioblastoma are similar; distinguishing between them is a diagnostic challenge.

    Xiu-Peng Zhang, Yang Liu, Di Zhang, Qin Zheng, Chen Wang, Liang Wang, Qing-Chang Li, Xue-Shan Qiu and En-Hua Wang

    Diagnostic Pathology 2017 12:28

    Published on: 20 March 2017

  3. Research

    Diagnostic accuracy of oral cancer cytology in a pilot study

    Recently, cytology has been applied to the diagnosis of oral lesions. We aimed to explore the diagnostic accuracy of oral cytology based on the histological diagnosis.

    Joji Sekine, Eiji Nakatani, Katsumi Hideshima, Teruaki Iwahashi and Hiroshi Sasaki

    Diagnostic Pathology 2017 12:27

    Published on: 16 March 2017

  4. Case Report

    Uterine epithelioid leiomyosarcoma with c-kit expression and YWHAE gene rearrangement: a case report of a diagnostic pitfall of uterine sarcoma

    Uterine sarcoma is a rare tumor that is often difficult to classify based on morphological and immunohistochemical analysis alone. Limited access to molecular biological analysis in routine practice would hind...

    Terufumi Kubo, Shintaro Sugita, Ryuichi Wada, Noriaki Kikuchi, Masahiro Iwasaki, Yumika Ito, Taro Sugawara, Hiromi Fujita, Makoto Emori, Ryoichi Tanaka, Hiroshi Hirano, Tsuyoshi Saito and Tadashi Hasegawa

    Diagnostic Pathology 2017 12:26

    Published on: 14 March 2017

  5. Research

    Implication of overexpression of dishevelled-associated activator of morphogenesis 1 (Daam-1) for the pathogenesis of human Idiopathic Pulmonary Arterial Hypertension (IPAH)

    Idiopathic pulmonary arterial hypertension (IPAH) is a rare, fatal disease of unknown pathogenesis. Evidence from our recent study suggests that IPAH pathogenesis is related to upregulation of the Wnt/planar c...

    Shun Yanai, Megumi Wakayama, Haruo Nakayama, Minoru Shinozaki, Hisayuki Tsukuma, Naobumi Tochigi, Tetsuo Nemoto, Tsutomu Saji and Kazutoshi Shibuya

    Diagnostic Pathology 2017 12:25

    Published on: 14 March 2017

  6. Research

    Evaluation of the correlation of vasculogenic mimicry, ALDH1, KiSS-1, and MACC1 in the prediction of metastasis and prognosis in ovarian carcinoma

    Recurrence and metastasis are the usual manifestations of treatment failure of epithelial ovarian carcinoma (EOC). Vasculogenic mimicry (VM; blood supply development often seen in highly aggressive cancers), a...

    Lan Yu, Bo Zhu, Shiwu Wu, Lei Zhou, Wenqing Song, Xiaomeng Gong and Danna Wang

    Diagnostic Pathology 2017 12:23

    Published on: 2 March 2017

  7. Erratum

    Erratum to: Quality of sweat test (ST) based on the proportion of sweat sodium (Na) and sweat chloride (Cl) as diagnostic parameter of cystic fibrosis: are we on the right way?

    Alethéa Guimarães Faria, Fernando Augusto Lima Marson, Carla Cristina de Souza Gomez, Maria Ângela Gonçalves de Oliveira Ribeiro, Lucas Brioschi Morais, Maria de Fátima Servidoni, Carmen Sílvia Bertuzzo, Eulália Sakano, Maura Goto, Ilma Aparecida Paschoal, Mônica Corso Pereira, Gabriel Hessel, Carlos Emílio Levy, Adyléia Aparecida Dalbo Contrera Toro, Andressa Oliveira Peixoto, Maria Cristina Ribeiro Simões…

    Diagnostic Pathology 2017 12:22

    Published on: 27 February 2017

    The original article was published in Diagnostic Pathology 2016 11:103

  8. Research

    HMGA2 immunostaining is a straightforward technique which helps to distinguish pulmonary fat-forming lesions from normal adipose tissue in small biopsies: a retrospective observational study about a series of 13 lung biopsies

    A tracheobronchial lesion observed during an endoscopic examination is usually sampled by the pulmonologist and sent to the pathologist for microscopic examination. Adipocytes may be observed in the lamina pro...

    Nicolas Piton, Émilie Angot, Florent Marguet and Jean-Christophe Sabourin

    Diagnostic Pathology 2017 12:21

    Published on: 23 February 2017

  9. Research

    Ki-67 as a controversial predictive and prognostic marker in breast cancer patients treated with neoadjuvant chemotherapy

    Studies have partly demonstrated the clinical validity of Ki-67 as a predictive marker in the neoadjuvant setting, but the question of the best cut-off points as well as the importance of this marker as a prog...

    Balázs Ács, Veronika Zámbó, Laura Vízkeleti, A. Marcell Szász, Lilla Madaras, Gyöngyvér Szentmártoni, Tímea Tőkés, Béla Á. Molnár, István Artúr Molnár, Stefan Vári-Kakas, Janina Kulka and Anna-Mária Tőkés

    Diagnostic Pathology 2017 12:20

    Published on: 21 February 2017

  10. Research

    Immunohistochemistry of sarcolemmal membrane-associated proteins in formalin-fixed and paraffin-embedded skeletal muscle tissue: a promising tool for the diagnostic evaluation of common muscular dystrophies

    The analysis of fresh frozen muscle specimens is standard following routine muscle biopsy, but this service is not widely available in countries with limited medical facilities, such as Thailand. Nevertheless,...

    Chinnawut Suriyonplengsaeng, Charungthai Dejthevaporn, Chaiyos Khongkhatithum, Suda Sanpapant, Nattha Tubthong, Koset Pinpradap, Nippa Srinark and Jariya Waisayarat

    Diagnostic Pathology 2017 12:19

    Published on: 20 February 2017

  11. Research

    Cytokeratin7 and cytokeratin19 expression in high grade cervical intraepithelial neoplasm and squamous cell carcinoma and their possible association in cervical carcinogenesis

    High risk human papillomavirus (HR HPV) infects cells at the squamocolumnar junction (SCJ) of the cervix, causing cancer. Cytokeratin (CK)7 is an SCJ marker, and stains cervical neoplasia. CK19 is a binding pa...

    Hojung Lee, Hyekyung Lee and Yong Kyun Cho

    Diagnostic Pathology 2017 12:18

    Published on: 17 February 2017

  12. Research

    Loss of chromosome 13 material in cellular angiofibromas indicates pathogenetic similarity with spindle cell lipomas

    Cellular angiofibroma is a rare benign mesenchymal neoplasm with morphological and immunohistochemical similarities to spindle cell lipoma. Karyotypic information on cellular angiofibroma is restricted to one ...

    Ioannis Panagopoulos, Ludmila Gorunova, Bodil Bjerkehagen, Kristin Andersen, Marius Lund-Iversen and Sverre Heim

    Diagnostic Pathology 2017 12:17

    Published on: 13 February 2017

  13. Research

    TP53 mutation-mediated genomic instability induces the evolution of chemoresistance and recurrence in epithelial ovarian cancer

    Genomic instability caused by mutation of the checkpoint molecule TP53 may endow cancer cells with the ability to undergo genomic evolution to survive stress and treatment. We attempted to gain insight into the p...

    Meiying Zhang, Guanglei Zhuang, Xiangjun Sun, Yanying Shen, Wenjing Wang, Qing Li and Wen Di

    Diagnostic Pathology 2017 12:16

    Published on: 2 February 2017

  14. Case Report

    An unusual case of Epstein-Barr virus-positive large B-cell lymphoma lacking various B-cell markers

    Epstein-Barr virus (EBV) is associated with B-cell lymphoma in various conditions, such as immunodeficiency and chronic inflammation. We report an unusual case of EBV-positive diffuse large B-cell lymphoma (DL...

    Shin-ichi Nakatsuka, Chikao Yutani, Masako Kurashige, Masaharu Kohara, Teruaki Nagano, Takayoshi Goto, Hiroyuki Takatsuka, Hidetaka Ifuku and Eiichi Morii

    Diagnostic Pathology 2017 12:15

    Published on: 31 January 2017

  15. Case Report

    Anastomosing hemangioma: report of two renal cases and analysis of the literature

    Anastomosing hemangioma (AH) is a very rare vascular tumor mimicking angiosarcoma, predominately observed in kidney and less frequently in other organs. We present two new renal cases of AH at opposite ends of...

    Marina Perdiki, Galateia Datseri, George Liapis, Nikolaos Chondros, Ioannis Anastasiou, Maria Tzardi, Johanna K. Delladetsima and Elias Drakos

    Diagnostic Pathology 2017 12:14

    Published on: 24 January 2017

  16. Research

    SESN2 correlates with advantageous prognosis in hepatocellular carcinoma

    SESN2 plays important roles in the regulation of cell survival, cell protection, and tumor suppression. However, the relationship between SESN2 expression and the clinicopathological attributes of hepatocellul...

    Shaosen Chen, Weigang Yan, Weiya Lang, Jing Yu, Li Xu, Xinyu Xu, Yunlong Liu and Hongguang Bao

    Diagnostic Pathology 2017 12:13

    Published on: 24 January 2017

  17. Case Report

    Epithelioid schwannoma of the skin displaying unique histopathological features: a teaching case giving rise to diagnostic difficulties on a morphological examination of a resected specimen, with a brief literature review

    Epithelioid schwannoma as a rare variant poses a challenge to all pathologists, as this uncommon entity is extremely difficult to conclusively diagnose by morphological analyses on a resected sample alone owin...

    Sohsuke Yamada, Mari Kirishima, Tsubasa Hiraki, Michiyo Higashi, Kazuhito Hatanaka and Akihide Tanimoto

    Diagnostic Pathology 2017 12:11

    Published on: 19 January 2017

  18. Case Report

    Immunohistochemical features of giant cell ependymoma of the filum terminale with unusual clinical and radiological presentation

    Giant cell ependymoma of the filum terminale is a rare variant, generally manifested as a well-circunscribed intradural mass with an indolent biological behavior.

    Fernando Candanedo-Gonzalez, Cindy Sharon Ortiz-Arce, Samuel Rosales-Perez, Ana Lilia Remirez-Castellanos, Candelaria Cordova-Uscanga and Armando Gamboa-Dominguez

    Diagnostic Pathology 2017 12:7

    Published on: 14 January 2017

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