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Figure 2 | Diagnostic Pathology

Figure 2

From: Stratification of non-small cell lung cancer patients for therapy with epidermal growth factor receptor inhibitors: the EGFR fluorescence in situ hybridization assay

Figure 2

Distinct types of EGFR gene amplification identified in non-small cell lung carcinomas using the EGFR SpectrumOrange/CEP 7 SpectrumGreen FISH probe (Vysis/Abbott Molecular): A. Large EGFR gene clusters; B. Co-localized clusters of EGFR and CEP7 signals; C. Large and bright EGFR signal, larger than the CEP 7 signals in tumor cells; D. High frequency of balanced EGFR and CEP 7 signals.

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