Marker | Thymoma Type |
---|
 | A | AB | B1 | B2 | B3 | MNT |
EMA | + | + | Focal | S | + | + |
CK7 | + | +^ | + | + | + | + |
CK20 | - | - | - | - | - | - |
CD57 | S | S | S | +* | +* | + |
CD5 | - | - | - | - | -/+ | - |
Bcl-2 | - | - | - | - | -/+ | - |
Calretinin | S | S | S | S | S | S |
Vimentin | + | + | - | - | - | - |
CD20 | + | + | - | - | - | - |
- MNT= micronodular thymoma
- S = single cells
- +^ = neoplastic epithelial cells in type B component were CK7 negative
- -/+ = variably (2 sporadic type B3 thymomas stained strongly positive)
- +* = strong expression in type B2 (n = 1) and type B3 (n = 3) thymomas associated with autoimmune disorder; scattered positive neoplastic cells in sporadic thymomas