|
Marker
|
Thymoma Type
|
|---|
| |
A
|
AB
|
B1
|
B2
|
B3
|
MNT
|
|
EMA
|
+
|
+
|
Focal
|
S
|
+
|
+
|
|
CK7
|
+
|
+^
|
+
|
+
|
+
|
+
|
|
CK20
|
-
|
-
|
-
|
-
|
-
|
-
|
|
CD57
|
S
|
S
|
S
|
+*
|
+*
|
+
|
|
CD5
|
-
|
-
|
-
|
-
|
-/+
|
-
|
|
Bcl-2
|
-
|
-
|
-
|
-
|
-/+
|
-
|
|
Calretinin
|
S
|
S
|
S
|
S
|
S
|
S
|
|
Vimentin
|
+
|
+
|
-
|
-
|
-
|
-
|
|
CD20
|
+
|
+
|
-
|
-
|
-
|
-
|
- MNT= micronodular thymoma
- S = single cells
- +^ = neoplastic epithelial cells in type B component were CK7 negative
- -/+ = variably (2 sporadic type B3 thymomas stained strongly positive)
- +* = strong expression in type B2 (n = 1) and type B3 (n = 3) thymomas associated with autoimmune disorder; scattered positive neoplastic cells in sporadic thymomas
