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Table 3 Immunohistochemical Results, Tumor Cell Expression

From: Thymomas: a cytological and immunohistochemical study, with emphasis on lymphoid and neuroendocrine markers

Marker Thymoma Type
  A AB B1 B2 B3 MNT
EMA + + Focal S + +
CK7 + +^ + + + +
CK20 - - - - - -
CD57 S S S +* +* +
CD5 - - - - -/+ -
Bcl-2 - - - - -/+ -
Calretinin S S S S S S
Vimentin + + - - - -
CD20 + + - - - -
  1. MNT= micronodular thymoma
  2. S = single cells
  3. +^ = neoplastic epithelial cells in type B component were CK7 negative
  4. -/+ = variably (2 sporadic type B3 thymomas stained strongly positive)
  5. +* = strong expression in type B2 (n = 1) and type B3 (n = 3) thymomas associated with autoimmune disorder; scattered positive neoplastic cells in sporadic thymomas