A 37 2/7 week gestational age male infant with Patau syndrome demonstrating alobar holoprosencephaly with cyclopia. A) Facial features included sloping forehead with a proboscis superior to a single central palpebral fissure. B) Close-up of the fused eyelids and proboscis showing a single nostril. C) Polydactyly showing six digits. D) Posterior view of the brain showing indistinct gyri, fusion of the hemispheres, and occipital encephalocele.E) Transposition of the aorta (A), and hypoplastic pulmonary trunk (P). F) Trisomy 13 [47, XY, +13] (karyotype by Giemsa-banding).