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Table 1 Comparison Between Immunophenotypes and Ultrastructural Features of Neoplastic Cells in Present Case and Lymphoid Tissue Phagocytic and Accessory Cells Neoplasms*

From: Primary histiocytic sarcoma arising in the head and neck with predominant spindle cell component

IM/US**

Case

HS

LCS

IDCS

FDCS

Lysozyme

++

++

+

+

+

CD163

++

N/A

N/A

N/A

N/A

CD68

++

++

+

+

+

S-100

+

+

++

++

+

CD1a

-

-

++

-

-

CD21

-

-

-

-

++

CD23

-

-

-

-

++

EMA

-

-

-

-

+

Fascin

N/A

-

-

-

+

Clusterin

N/A

-

-

-

++

CD45

+

+

+

+

++

CD3

-

-

-

-

-

CD4

+

+

+

-

-

CD20

-

-

-

-

-

MHC II

N/A

+

++

+

-

Lysosomes

Numerous

Numerous

Variable

Scattered

Scattered

Birbeck granules

-

-

++

-

-

Desmosomes

-

-

-

-

++

IDCP***

-

-

-

++

-

  1. * References: 1, 5, 6, 10–12
  2. ** IM/US: Immunohistochemical marker/ultrastructure
  3. ***IDCP: Interdigitating cell processes
  4. +: weak
  5. ++: strong
  6. HS: Histiocytic sarcoma
  7. LCS: Langerhans cell sarcoma
  8. IDCS: Interdigitating dendritic cell sarcoma
  9. FDCS: Follicular dendritic cell sarcoma
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Diagnostic Pathology

ISSN: 1746-1596

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