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Table 1 Clinical data and histology of Medullomyoblastoma

From: The role of immunohistochemistry in medullomyoblastoma – a case series highlighting divergent differentiation

Case No. Age#/Sex Presentation Duration of symptoms (days) Imaging (CT/MRI) Histopathological features
1 28 y/M Headache, vomiting, ataxic gait 14 Posterior fossa SOL Predominant areas of PNE cells, nodules of cells showing smooth muscle differentiation, cartilaginous islands
2 6 mon/F Vomiting, altered sensorium 15 Posterior fossa SOL, hydrocephalus Predominant areas of PNE cells, RMB areas present, focal cartilaginous and epithelial differentiation
3 4 y/M Recurrent headache, vomiting 20 Posterior fossa contrast enhancing SOL Co-dominant RMB and PNE areas, many strap cells present
4 3 y/M Headache, vomiting, altered sensorium 20 Posterior fossa SOL Predominant areas of PNE cells, RMB areas present with strap cells
5 4 y/M Persistant vomiting 60 Posterior fossa SOL, hydrocephalus Predominant areas of PNE cells, RMB areas with strap cells present
6 8 y/M Headache, vomiting, vertigo 60 Posterior fossa SOL Predominant areas comprise of larger atypical cells with vesicular nuclei and moderate amount of cytoplasm, no typical strap cells present, rest of the areas show PNE cells
7 4 y/M Vomiting, altered sensorium 30 Posterior fossa SOL Predominant areas of PNE cells, RMB areas show strap cells
  1. PNE – Primitive neuroectodermal; RMB – Rhabdomyoblastic; SOL – Space occupying lesion; Age# y – years & mon-months