Melanotic medullary carcinoma of thyroid – report of a rare case with brief review of literature

Diagnostic Pathology

Table 2 Summary and comparison of immunohisochemical profile of the previously reported cases

IHC	Present case	*3	*4	*5	*6	*7	*8	*9	*10	*11
Calcitonin	+	+	+	+	+	+	+	+	+	+
HMB-45/Melanin stain	+	+	+	+	+	+	+	-	+	+
Carcinoembryonic antigen	+				+			+
Synaptophysin	+
Chromogranin	+				+		+	+		+
Epithelial membrane antigen	+
Vimentin	+
Cytokeratin	+							+	+
S-100	-				-		+	+	+
Melan-A	-

ISSN: 1746-1596