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Table 2 Correlation between MMP-13 expression and clinicopathological parameters of chondrosarcoma patients.

From: Is collagenase-3 (MMP-13) expression in chondrosarcoma of the jaws a true marker for tumor aggressiveness?

Parameter

No. of patients

MMP-13 immunostaining

P-value

  

MMP-13 (-ve) (n = 3) %

MMP-13 (+ve) (n = 8) %

 

Age

    

   >60

6

2 (33.3%)

4(66.7%)

 

   ≤ 60

5

1 (20%)

4 (80%)

NS

Sex

    

   Male

7

2 (28.6%)

5(71.4%)

 

   Female

4

1 (25%)

3(75%)

NS

Site

    

   Mandible

8

2 (25%)

6(75%)

 

   Maxilla

3

1 (33.3%)

2(66.7%)

NS

Mitosis

    

   0

3

3 (100%)

0(0%)

 

   1

4

0(0%)

4(100%)

 

   2

2

0(0%)

2(100%)

*S

   3

2

0 (0%)

2 (100%)

 

Necrosis

    

   o

5

3 (60%)

2 (40%)

 

   1

4

0 (0%)

4 (100%)

*S

   2

2

0 (0%)

2 (100%)

 

Grades

    

   G-I

4

3 (75%)

1 (25%)

 

   G-II

5

0 (0%)

5 (100%)

*S

   G-III

2

0 (0%)

2 (100%)

 

Recurrence

    

   +

3

0(0%)

3 (100%)

 

   -

8

3 (37.5%)

5 (62.5%)

NS

  1. P ≤ 0.05 means significant difference
  2. *S = Signficant
  3. NS = Not significant
  4. Necrosis Non = "0", <50% = "1", ≥ 50% = "2".
  5. Mitosis 0–9/10HPF = "1", 10–19/10HPF = "2", ≥ 20/10HPF = "3"