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Table 2 Correlation between MMP-13 expression and clinicopathological parameters of chondrosarcoma patients.

From: Is collagenase-3 (MMP-13) expression in chondrosarcoma of the jaws a true marker for tumor aggressiveness?

Parameter No. of patients MMP-13 immunostaining P-value
   MMP-13 (-ve) (n = 3) % MMP-13 (+ve) (n = 8) %  
Age     
   >60 6 2 (33.3%) 4(66.7%)  
   ≤ 60 5 1 (20%) 4 (80%) NS
Sex     
   Male 7 2 (28.6%) 5(71.4%)  
   Female 4 1 (25%) 3(75%) NS
Site     
   Mandible 8 2 (25%) 6(75%)  
   Maxilla 3 1 (33.3%) 2(66.7%) NS
Mitosis     
   0 3 3 (100%) 0(0%)  
   1 4 0(0%) 4(100%)  
   2 2 0(0%) 2(100%) *S
   3 2 0 (0%) 2 (100%)  
Necrosis     
   o 5 3 (60%) 2 (40%)  
   1 4 0 (0%) 4 (100%) *S
   2 2 0 (0%) 2 (100%)  
Grades     
   G-I 4 3 (75%) 1 (25%)  
   G-II 5 0 (0%) 5 (100%) *S
   G-III 2 0 (0%) 2 (100%)  
Recurrence     
   + 3 0(0%) 3 (100%)  
   - 8 3 (37.5%) 5 (62.5%) NS
  1. P ≤ 0.05 means significant difference
  2. *S = Signficant
  3. NS = Not significant
  4. Necrosis Non = "0", <50% = "1", ≥ 50% = "2".
  5. Mitosis 0–9/10HPF = "1", 10–19/10HPF = "2", ≥ 20/10HPF = "3"