Figure 3

(A):Touch imprint of ALTCL case showing large atypical lymphoid cells with vesicular nuclei and prominent nucleoli (modified PAP, 400 ×), (B): ALTCL case showing Diffuse infiltration by large atypical lymphoid cells with horse-shoe nuclei and prominent nucleoli. Binucleated RS-like cells are encountered (arrow) (H & E, 400 ×)., (C) Malignant cells show positive reaction to CD 3, (D) Large anaplastic cells are positive for CD 30, (E): FCM dot plots of a case of ALTCL showing (i) Large FSc (ii) Negative isotype control (iii, iv) Atypical population showing positive reaction to CD45, CD 3, (v) Some of the CD45RO positive cells (T-cells)are positive for CD30 (vi) Positive cells for CD 30 have large FSc.