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Table 2 Expression of EBV and Topo II in the normal oral tissues, oral epithelial dysplasia and oral squamous cell carcinomas

From: The significance of Epstein Barr Virus (EBV) & DNA Topoisomerase II alpha (DNA-Topo II alpha) immunoreactivity in normal oral mucosa, Oral Epithelial Dysplasia (OED) and Oral Squamous Cell Carcinoma (OSCC)

HISTOLOGY

Number of cases

EBV expression(%)(a)

P-value

Topo II- LI (%)(b)

P-value

NSE

20

0.000 ± 0.000

d

5.35 ± 2.22

c

OED

16

25.6 ± 25.38

 

14.08 ± 2.99

 

Mild

7

13.43 ± 13.24

NS

12.27 ± 2.17

NS

Moderate

5

24.00 ± 22.62

 

13.50 ± 1.86

 

Severe

4

48.75 ±

 

17.98 ± 1.51

 

OSCC

22

41.79 ± 29.31

 

27.56 ± 7.49

 

W-scc

10

36.09 ± 22.37

 

22.40 ± 3.19

 

M-scc

8

41.15 ± 33.18

NS

28.54 ± 4.84

e

P-scc

4

57.33 ± 38.91

 

39.00 ± 6.45

 
  1. NSE, normal squamous epithelium; OED, OraLepithelial dysplasia; OSCC, oral squamous cell carcinoma; NS, not significant.
  2. a mean ± standered deviation of EBV
  3. b mean ± standered deviation of Topo II-α LI.
  4. c NSE vs. OED P < 0.001;NSE vs. SCC, P < 0.001; OED vs. SCC, P = 0.083.
  5. dNSE vs. OED P < 0.001;NSE vs. SCC, P < 0.001; OED vs. SCC, P < 0.001.
  6. eW-SCC vs. M-SCC, P = 0.008; W-SCC 1 vs.P-SCC, P = 0.001; W-SCC vs. M-SCC +P-SCC, P < 0.001.