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Table 3 Expression of EBV and Topo II in relation to clinicopathological parameters in oral squamous cell carcinoma

From: The significance of Epstein Barr Virus (EBV) & DNA Topoisomerase II alpha (DNA-Topo II alpha) immunoreactivity in normal oral mucosa, Oral Epithelial Dysplasia (OED) and Oral Squamous Cell Carcinoma (OSCC)

Parameter

Total n.

EBV

P-value

Topo II-

P-value

Stage T

22

    

T1

8

29.24 ± 46.00

0.191

24.68 ± 5.96

0,038

T2

10

50.36 ± 30.71

 

26.38 ± 5.22

 

T3

4

45.48 ± 37.79

 

36.78 ± 9.39

 

N stage

22

    

N-

9

23.59 ± 23.71

0.009

23.04 ± 3.95

0.002

N+

13

54.39 ± 26.62

 

30.84 ± 7.80

 

Differentiation

22

    

Well-diff.

10

36.09 ± 22.37

0.208

22.40 ± 3.19

 

Moderate-diff

8

41.15 ± 33.18

 

28.54 ± 4.84

0.000

Poorly-diff.

4

57.33 ± 38.91

 

39.00 ± 6.45