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Table 3 Expression of EBV and Topo II in relation to clinicopathological parameters in oral squamous cell carcinoma

From: The significance of Epstein Barr Virus (EBV) & DNA Topoisomerase II alpha (DNA-Topo II alpha) immunoreactivity in normal oral mucosa, Oral Epithelial Dysplasia (OED) and Oral Squamous Cell Carcinoma (OSCC)

Parameter Total n. EBV P-value Topo II- P-value
Stage T 22     
T1 8 29.24 ± 46.00 0.191 24.68 ± 5.96 0,038
T2 10 50.36 ± 30.71   26.38 ± 5.22  
T3 4 45.48 ± 37.79   36.78 ± 9.39  
N stage 22     
N- 9 23.59 ± 23.71 0.009 23.04 ± 3.95 0.002
N+ 13 54.39 ± 26.62   30.84 ± 7.80  
Differentiation 22     
Well-diff. 10 36.09 ± 22.37 0.208 22.40 ± 3.19  
Moderate-diff 8 41.15 ± 33.18   28.54 ± 4.84 0.000
Poorly-diff. 4 57.33 ± 38.91   39.00 ± 6.45