Autoantibodies | Associated CTD | Sensitivity | Specificity |
---|---|---|---|
ANA | SLE | 93 | 57 |
 | Sjogren's syndrome | 48 | 52 |
 | SS | 85 | 54 |
 | PM/dermatomyositis | 61 | 63 |
 | Raynaud phenomena | 64 | 41 |
Specific ANA | Â | Â | Â |
Anti-dsDNA | SLE | 57 | 97 |
Anti-Sm | SLE | 25–30 | High* |
Anti-SSA/Ro | Sjogren's syndrome, subacute cutaneous SLE, Neonatal lupus syndrome | 8–70 | 87 |
Anti-SSB/La | Sjogren's syndrome, subacute cutaneous SLE, Neonatal lupus syndrome | 16–40 | 94 |
Anti-U3-RNP | SS | 12 | 96 |
Anticentromere | Limited cutaneous SS | 65 | 99.9 |
Scl-70 | SS | 20 | 100 |
Jo-1 | PM | 30 | 95 |