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Table 3 Common IF-ANA patterns associated with specific diseases

From: Antinuclear antibodies and their detection methods in diagnosis of connective tissue diseases: a journey revisited

ANA pattern Antigen Associated diseases
Speckled ENA, RNP, Sm, SSA/Ro, SSB/La, Scl-70, Jo-1, ribosomal-P SLE, Mixed CTD, SS, Primary Sjogren's syndrome, PM
Homogenous dsDNA, Histones SLE, Drug induced SLE
Peripheral (rim) RNP, Sm, SSA/Ro SLE, SS
Nucleolar Anti-PM-Scl, anti-RNA polymerase I-III, anti-U3-RNP, To RNP SS, PM
Centromere CENP A-E Limited SS