Skip to main content

Table 1 Immunohistochemical analysis of p16INK4A expression in tissue microarray cores from 806 cervix biopsies containing normal tissues, CIN1, CIN2, CIN3, and invasive cervical carcinoma (ICC), evaluated using the simple protocol.

From: p16 as a diagnostic marker of cervical neoplasia: a tissue microarray study of 796 archival specimens

  

p16INK4A immunostaining

 

n

Negative*

Positive#

Normal cervix

10

10 (100.0)

0 (0)

CIN1

249

69 (27.7)

180 (72.3)

CIN2

233

21 (9.0)

212 (91.0)

CIN3

181

3 (1.7)

178 (98.3)

ICC

133

2 (1.5)

131 (98.5)

  1. *Negative: no staining or weak staining in less than 10% of epithelial cells.
  2. #Positive: moderate or strong staining in more than 10% of epithelial cells.
Back to article page

Diagnostic Pathology

ISSN: 1746-1596

Contact us