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Table 1 The B-Classification and the histologic expression

From: Integration and acceleration of virtual microscopy as the key to successful implementation into the routine diagnostic process

Classification Definition
B1
normal
Normal or not interpretable tissue
- benign parenchyma with or without minimal changes
- artifacts, bleeding
B2
Benign
Benign Lesion
- fibrocystic changes
- fibro adenoma
- sclerosing adenosis
-ectasia, abscess, fat tissue necrosis
- small intraductal papilloma
B3
benign, but with increased risk of malignancy or an association with a malignant tumor
Lesion with uncertain malignant potential
- large or multiple papillary lesions with or without atypia
- scar, complex sclerosing lesion
- lobular intraepithelial neoplasia (LIN)
- ADH
- phylloid tumor or unclear fibroepithelial tumor
B4
suspect
Suspect for malignancy
B5
malignant
Malignant Lesions
a) ductal Carcinoma in situ (DCIS)
LIN (CLIS) of pleomorphic subtype G3
LIN with comedo necrosis
b) Carcinoma
c) status of invasion not decidable
d) other malignant tumor such as Lymphoma, metastasis or sarcoma