Table 2 Literature Review of Giant Cell Tumor of Urinary Bladder
Authors | Age/sex | Expression of histiosytic markers and vimentin in MC | Expression of epithelial markers in MC | Associated malignancies | Treatment | Outcome |
|---|---|---|---|---|---|---|
Holtz et al [7] | 79/M | NA | NA | UC | TUR | Death at 33 months (unrelated cause) |
Kitazawa et al [8] | 67/M | NA | NA | UC, noninvasive | TUR | NED (8 months) |
Ligdi et al [9] | 67/F | NA | Keratin (-) EMA (-) | UC, noninvasive | TUR | NED (18 months) |
Amir and Rosermann [10] | 74/M | Vimentin (+) | Keratin (-) EMA (-) | UC, noninvasive | NA | NA |
69/M | Vimentin (+) | Keratin (-) EMA (-) | UC, noninvasive | NA | NA | |
O'Conner et al [11] | 73/F | NA | NA | None | TUR, Anterior pelvic | Exenteration+ vaginectomy |
Baydar et al [12] | 81/M | CD68 (+) | Keratin (-) EMA (-) | UC, noninvasive | TUR | NA |
81/M | CD68 (+) | Keratin (-) EMA (-) | UC, noninvasive | TUR | Alive, recurrent UC (4 months) | |
67/M | CD68 (+) | Keratin (-) EMA (+) | UC, noninvasive | Radical cystectomy | Death at 1 year | |
Behzatoglu et al (New cases) | 56/M | CD68 (+) Vimentin (+) SMA (+) | Keratin (-) EMA (-) | None | TUR | NED (35 months) |
74/M | CD68 (+) Vimentin (+) | Keratin (-) EMA (-) | UC, noninvasive | TUR | NED (42 months) |