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Table 2 Literature Review of Giant Cell Tumor of Urinary Bladder

From: Giant cell tumor-like lesion of the urinary bladder: a report of two cases and literature review; giant cell tumor or undifferentiated carcinoma?

Authors Age/sex Expression of histiosytic markers and vimentin in MC Expression of epithelial markers in MC Associated malignancies Treatment Outcome
Holtz et al [7] 79/M NA NA UC TUR Death at 33 months (unrelated cause)
Kitazawa et al [8] 67/M NA NA UC, noninvasive TUR NED (8 months)
Ligdi et al [9] 67/F NA Keratin (-)
EMA (-)
UC, noninvasive TUR NED (18 months)
Amir and Rosermann [10] 74/M Vimentin (+) Keratin (-)
EMA (-)
UC, noninvasive NA NA
  69/M Vimentin (+) Keratin (-)
EMA (-)
UC, noninvasive NA NA
O'Conner et al [11] 73/F NA NA None TUR,
Anterior pelvic
Exenteration+
vaginectomy
Baydar et al [12] 81/M CD68 (+) Keratin (-)
EMA (-)
UC, noninvasive TUR NA
  81/M CD68 (+) Keratin (-)
EMA (-)
UC, noninvasive TUR Alive, recurrent UC (4 months)
  67/M CD68 (+) Keratin (-)
EMA (+)
UC, noninvasive Radical cystectomy Death at 1 year
Behzatoglu et al
(New cases)
56/M CD68 (+)
Vimentin (+)
SMA (+)
Keratin (-)
EMA (-)
None TUR NED (35 months)
  74/M CD68 (+)
Vimentin (+)
Keratin (-)
EMA (-)
UC, noninvasive TUR NED (42 months)
  1. UC, urothelial carcinoma; NED, no evidence of disease; NA, not available; MC, mononuclear cells