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Table 3 Immunohistochemical and FISH data

From: Overexpression of c-erb B2 is a negative prognostic factor in anaplastic astrocytomas

Case no. c-erb B-1
(clone EGFR.25) (internal domain)
c-erb B-1
(clone EGFR.113) (external domain)
c-erb B-2
(clone CB11) (internal domain)
c-erb B-2
(clone 3B5) (internal domain)
c-erb B-2
(clone 5A2)
(internal domain)
c-erb B-3 c-erb B-4 EGFR gene amplification (FISH)
1 9 9 4 6 6 9 4 Yes
2 9 1 0 9 3 4 2 No
3 6 0 4 3 1 9 0 No
4 6 1 1 9 0 0 0 No
5 0 0 4 6 2 6 4 No
6 1 9 1 4 0 4 0 Yes
7 9 9 0 1 0 0 0 No
8 6 2 0 6 4 6 4 Yes
9 9 9 2 6 0 6 6 No
10 9 9 0 9 1 9 4 Yes
11 4 0 2 6 0 4 4 Yes
12 9 4 0 6 2 9 2 Yes
13 9 2 4 6 1 9 2 No
14 4 0 0 1 0 0 0 No
15 2 1 0 9 1 6 0 No
16 6 0 0 4 0 6 1 No
17 9 2 0 9 4 9 2 No
18 4 1 6 9 1 4 4 No
19 4 0 0 1 0 4 0 Yes
20 6 1 1 6 0 6 1 Yes
21 6 4 1 6 0 4 2 No
22 9 6 2 6 6 4 2 No
23 9 3 0 6 0 1 0 No
24 6 0 0 6 3 6 2 No
25 6 2 1 6 3 9 2 No
26 6 4 6 6 2 4 1 Yes
27 6 0 0 1 0 2 1 No
28 6 1 0 4 0 4 1 No
29 9 6 0 4 0 0 1 No
30 3 0 0 4 0 2 2 No
31 6 1 0 9 3 9 6 No
Median Staining Index 6 1 0 6 1 4 2  
No. of positive cases/Total no. of cases 30/31 22/31 14/31 31/31 16/31 27/31 23/31 9/31
Percentage positivity 97% 71% 45% 100% 52% 97% 74% 29%