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Table 3 Localization and immunostaining intensity of VEGF expression in placental villous tissues

From: Intrauterine growth restriction and placental angiogenesis

  Normal pregnancy
(n: 55)
IUGR
(n: 55)
Statistical comparison
P value
Score 0
n (%)
1+
n (%)
2+
n (%)
3+
n (%)
0
n (%)
1+
n (%)
2+
n (%)
3+
n (%)
P*
CVSC - 55 (100) - - - - - 55 (100) <0.001
VSMC - 55 (100) - - - - - 55 (100) <0.001
VVEC - 55 (100) - - - - - 55 (100) <0.001
ST - 55 (100) - - - - - 55 (100) <0.001
CT - 55 (100) - - - - - 55 (100) <0.001
EVT   55 (100) - - - - - 55 (100) <0.001
  1. IUGR: Intrauterine growth restricted; CVSC: Chorionic villous stromal cells; VSMC: Vascular smooth muscle cells; VVEC: Villous vascular endothelial cells; ST: Syncytiotrophoblasts; CT; Cytotrophoblasts; EVT: Extravillous trophoblasts [Staining intensity of VEGF were scored as follows: 0 (negative), weak (1+), moderate (2+), and strong (3+)] *P: Statistical comparison of normal and IUGR placental tissues