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Table 2 Summary of phenotypical expression analysis by immunohistochemical examination

From: Duodenal gangliocytic paraganglioma showing lymph node metastasis: A rare case report

 

Literature summary*

Present case

 

Epithelioid cell

Spindle-Shaped cell

Ganglion-like cell

Epithelioid cell

Spindle-Shaped cell

Ganglion-like cell

CD56

NR

NR

NR

+

-

+

Chromogranin A

4/4

0/2

1/2

-

-

-

Somatostatin

3/3

0/1

2/2

+

-

+

Synaptophysin

4/4

1/3

3/3

+

-

+

S-100

1/2

6/6

0/2

-

+

-

CK

1/1

NR

NR

-

-

-

NF

1/2

2/3

1/2

ND

ND

ND

NSE

3/3

3/3

2/2

ND

ND

ND

PP

1/2

0/1

2/2

ND

ND

ND

bcl-2

NR

NR

NR

-

-

-

p53

NR

NR

NR

-

-

-

  1. CK: Cytokeratin, NF: Neurofilament, NSE: Neuron-specific enolase, PP: Pancreatic polypeptide
  2. NR: Not reported, ND: Not done in the present case.
  3. *: Based on referenced [1, 16–19], and [21].
  4. In the present case, three identical components have been clearly identified by phenotypical expression analysis, which corresponds to those previously reported with the exception for chromogranin A. Furthermore, we found lymph node metastasis despite lack of bcl-2 and p53 expression.
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Diagnostic Pathology

ISSN: 1746-1596

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