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Table 4 Association between immunostaining and Fuhrman grade and stage.

From: Evaluation of neuroendocrine markers in renal cell carcinoma

   Immunostaining  
Fuhrman grade or stage Marker immunonegative, n (%) immunopositive, n (%) p-value
grade I serotonin 5 (100) 0 (0) 0.2
grade II   75 (95) 4 (5)  
grade III   31 (84) 6 (16)  
grade IV   20 (91) 2 (9)  
stage I serotonin 60 (91) 6 (9) 0.6
stage II   9 (90) 1 (10)  
stage III   45 (90) 5 (10)  
stage IV   19 (100) 0 (0)  
grade I CD56 5 (100) 0 (0) 0.7
grade II   65 (83) 13 (17)  
grade III   29 (78) 8 (22)  
grade IV   17 (77) 5 (23)  
stage I CD56 59 (88) 8 (12) 0.2
stage II   7 (70) 3 (30)  
stage III   38 (78) 11 (22)  
stage IV   14 (78) 4 (22)  
grade I NSE 0 (0) 5 (100) 0.1
grade II   41 (52) 38 (48)  
grade III   22 (56) 17 (44)  
grade IV   11 (55) 9 (45)  
stage I NSE 35 (52) 32 (48) 0.6
stage II   6 (55) 5 (45)  
stage III   28 (57) 21 (43)  
stage IV   7 (39) 11 (61)