Figure 1From: Identification of tissue of origin in carcinoma of unknown primary with a microarray-based gene expression testTissue of Origin Test workflow and results. RNA from frozen tissue is extracted, amplified, and biotin-labeled before hybridization to a Pathchip™ microarray. Gene expression data are then analyzed and a report indicating the studied tissue's molecular similarity to established profiles for 15 tissues of origin is produced.Back to article page