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Figure 3 | Diagnostic Pathology

Figure 3

From: Renal oncocytoma: a comparative clinicopathologic study and fluorescent in-situ hybridization analysis of 73 cases with long-term follow-up

Figure 3

Spectrum of chromosomal abnormalities in renal oncocytomas observed in our study using fluorescent in-situ hybridization panel. In addition to isolated loss of chromosome 1, a wide variety of combined losses was detected. The previously described chromosomal profile (no abnormalities or isolated loss of chromosome 1) could possibly distinguish renal oncocytoma from ChRCC; however, these were seen in only 30% of renal oncocytomas in our study. In contrary, one of the ChRCCs with typical morphology and positivity for Hale's colloidal iron showed no chromosomal abnormalities.

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