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Table 1 Association of VEGF, PTEN expression and MVD with tumor grade in laryngeal carcinoma (mean ± standard error of mean).

From: Poor prognostic clinicopathologic features correlate with VEGF expression but not with PTEN expression in squamous cell carcinoma of the larynx

  

PTEN

 

VEGF

   
 

N(%)

Negative

Mild

Severe

P

Negative

Mild

Severe

P

MVD*

P

Grade

    

0.400

   

0.015

 

0.003

   Grade 1

76

11(14)

27(36)

38(50)

 

7(9)

18(24)

51(67)

 

43.0 ± 2.6

 

   Grade 2

41

6(15)

11(27)

24(58)

 

2(5)

10(24)

29(71)

 

40.4 ± 2.8

 

   Grade 3

23

9(39)

5(22)

9(39)

 

1(4)

 

22(96)

 

59.5 ± 5.8

 

Total (%)

140

26(18)

43(31)

71(51)

 

10(7)

28(20)

102(73)

   
  1. *p: grade 1 vs 3 = 0.007; grade 2 vs 3 = 0.04; MVD, microvessel density; PTEN, phosphatase and tensin homolog deleted in chromosome ten; VEGF, vascular endothelial growth factor;