Figure 7
Detection of apoptotic cells in subcutaneous tumors by TUNEL assay and immunohistochemical staining for caspase 3. (A) TUNEL assay detecting apoptotic cells (arrows) using stable transfectant cells with an empty vector (KYSE 170 mock) and with a siRNA vector against fascin (KYSE 170F4). (B) Photomicrographs of immunohistochemical staining detected active caspase 3 pattern (arrows) in the in vivo model tumor using stable transfectant cells with an empty vector (KYSE 170 mock) and with a siRNA vector against fascin (KYSE 170F4).