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Table 2 Summary of biomarker expression for the second whole tissue section quantification

From: Tissue microarrays: one size does not fit all

   Distribution of expression values
Biomarker Quantitation
Method*
0%
(min)
10% 25% 50%
(median)
75% 90% 100%
(max)
B7-H1 % 0 0 0 0 0 0 10
B7-H3 % 0 0 0 0 0 5 100
IMP3 % 0 0 0 0 0 10 80
CAIX % 0 20 100 100 100 100 100
Survivin mm2 0.65 1.95 2.61 4.56 12.38 25.41 82.08
Ki-67 mm2 0.65 2.61 12.05 24.76 41.69 68.08 329.64
  1. *The membranous and cytoplasmic staining patterns of B7-H1, B7-H3, IMP3, and CAIX were quantitated as the percentage of positive tumor cells in 5-10% increments, whereas the nuclear staining patterns of survivin and KI-67 were quantitated as the number of positive tumor cells per mm2.