CLINIPATHOLOGYCAL FINDINGS - CHRONOLOGY | |||
---|---|---|---|
DATE | June 2007 | July 2008 | February 2009 |
LOCATION | Mass in the right elbow | Intratesticular tumor | Patient died with multiple metastases in the left thigh, lung and mediastinum. No autopsy was performed |
HISTOLOGY | Eosinophilic hyalinizing sclerosing matrix with small round cells | Fusocellular RMS with eosinophilic matrix and rhabdomyoblasts | |
MITOSIS | 4 mit/10HPF | 10mit/10HPF | |
IHC (+) | Vimentin | Vimentin | |
MyoD1 | MyoD1 | ||
SMA | SMA | ||
CD99 | CD99 | ||
myogenin | |||
MIB-1 | 25-30% | 20% | |
RT-PCR | PAX3-FKHR and PAX7-FKHR were not found. | PAX3-FKHR and PAX7-FKHR were not found. | |
FISH | FOXO1A (-) | FOXO1A (-) | |
Chemotherapy | CTX+VCR+Doxorrubicin | Ifosfamide | |
Surgery | Tumor resection | Right Orquidectomy |