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Figure 2 | Diagnostic Pathology

Figure 2

From: Two cases of breast carcinoma with osteoclastic giant cells: Are the osteoclastic giant cells pro-tumoural differentiation of macrophages?

Figure 2

Topography of CD68-positive cells and expression of VEGF and MMP12. Case 1 and Case 2 showed distinct vascular patterns, but in both cases OGCs preferentially appeared in hypervascular stroma. Marked expression of VEGF and MMP12 was evident. A: Distribution of blood vessels marked with CD31 in Case 1. B, C: CD68-positive cells in Case 1. D: Distribution of blood vessels marked with CD31 in Case 2. E, F: CD68-positive cells in Case 2. G-R: VEGF and MMP12 expression in Case 1 (G-L), and Case 2 (M-R).

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