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Table 4 Sensitivity, Specificity, Positive (PPV) and Negative (NPV) Predictive Values of the different immunomarkers (%)

From: Diagnostic utility of snail in metaplastic breast carcinoma

Stains vs. Case N Overall
Agreement, %
(95% CI)
Sensitivity, % (95% CI) Specificity, % (95% CI) PPV NPV
EGFR 60 65.0 (52.4, 75.8) 100.0 (89.9, 100.0) 19.2 (8.5, 37.9) 61.8 100.0
OSCAR 60 88.3 (77.8, 94.2) 85.3 (69.9, 93.6) 92.3 (75.9, 97.9) 93.6 82.8
P63 60 81.7 (70.1, 89.4) 67.6 (50.8, 80.9) 100.0 (87.1, 100.0) 100.0 70.3
SNAIL 60 58.3 (45.7, 71.8) 100.0 (89.9, 100.0) 3.8 (0.7, 18.9) 57.6 100.0
WSKER 60 86.7 (75.8, 93.1) 76.5 (60.0, 87.6) 100.0 (87.1, 100.0) 100.0 76.5
OSCAR & P63 & WSKER 60 90.0 (79.9, 95.3) 88.2 (73.4, 95.3) 92.3 (75.9. 97.9) 93.8 85.7
OSCAR & WSKER 60 88.3 (77.8, 94.2) 85.3 (69.9, 93.5) 92.3 (75.9, 97.9) 93.6 82.8
OSCAR & P63 60 90.0 (79.9, 95.3) 88.2 (73.4, 95.3) 92.3 (75.9. 97.9) 93.8 85.7
P63 & WSKER 60 90.0 (79.9, 95.3) 82.4 (66.5, 91.7) 100.0 (87.1, 100.0) 100.0 81.2
  1. EGFR = epidermal growth factor receptor; WS-KER = wide spectrum keratin