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Table 5 Correlation between the use of antiretroviral therapy and immunohistochemical, morphometric and viral load data.

From: Histomorphometric and immunohistochemical analysis of infectious agents, T-cell subpopulations and inflammatory adhesion molecules in placentas from HIV-seropositive pregnant women

 

THERAPY +

THERAPY -

p VALUE

ICAM1+

15

12

0.0322

CD8 + MEDIAN

1.75

1.5

0.6324

AREA MEDIAN

3711.84

3972.13

0.2940

PERIMETER MEDIAN

243.21

248.66

0.5580

MEDIAN OF 3 VIRAL LOAD

5841.67

19446.67

0.0165

TOTAL

35

16

 
  1. KEY: therapy += patients who had antiretroviral therapy for at least 1 month before giving birth; therapy - = patients who only had loading doses or did not undergo antiretroviral therapy; ICAM-1+ = number of cases with immunohistochemical expression of ICAM-1; median CD8+ = median CD8+ T cell count; median area/perimeter = median of area and perimeter in microns of placental villi; median of 3 viral loads = median of the three first viral loads; p = confidence interval of less than 0.05.