clinical- pathological characteristic | Copy number | Expression | ||||
---|---|---|---|---|---|---|
 | Positive, N/% | Negative, N/% | P value | Positive, N/% | Negative, N/% | P value |
Age(years) | Â | Â | Â | Â | Â | Â |
≤35 | 5/10.9 | 4/4.3 | 0.265c | 23/92.0 | 107/93.9 | 1.000c |
>35 | 41/89.1 | 89/95.7 | Â | 2/8.0 | 7/6.1 | Â |
Lymph node metastasis | Â | Â | Â | Â | Â | Â |
Positive | 23/50 | 49/52.7 | 0.765a | 16/64.0 | 56/49.1 | 0.178a |
Negative | 23/50 | 44/47.3 | Â | 9/36.0 | 58/50.9 | Â |
Stage | Â | Â | Â | Â | Â | Â |
0 | 0/0 | 2/2.2 | 0.748a, $ | 1/4.0 | 2/1.8 | 0.450a, $ |
I | 10/21.7 | 18/19.4 | Â | 6/24.0 | 21/18.4 | Â |
II | 25/54.3 | 53/57 | Â | 11/44.0 | 67/58.8 | Â |
III | 10/21.7 | 20/21.5 | Â | 7/28.0 | 22/20.2 | Â |
IV | 1/2.2 | 0/0 | Â | 0/0 | 1/0.9 | Â |
Tumor type | Â | Â | Â | Â | Â | Â |
DCIS | 0/0 | 3/3.2 | 0.551b, & | 1/4.0 | 2/1.8 | 1.000c, & |
LCIS | 0/0 | 0/0 | Â | 0/0 | 0/0 | Â |
IDC | 44/95.7 | 83/89.2 | Â | 23/92.0 | 104/91.2 | Â |
ILC | 0/0 | 3/3.2 | Â | 0/0 | 3/2.6 | Â |
Other | 2/4.3 | 4/4.3 | Â | 1/4.0 | 5/4.4 | Â |
ER | Â | Â | Â | Â | Â | Â |
Positive | 33/71.7 | 72/77.4 | 0.464a | 13/52.0 | 92/80.7 | 0.002a |
Negative | 13/28.3 | 21/22.6 | Â | 12/48.0 | 22/19.3 | Â |
PR | Â | Â | Â | Â | Â | Â |
Positive | 27/58.7 | 54/58.1 | 0.943a | 5/20.0 | 76/66.7 | 0.000a |
Negative | 19/41.3 | 39/41.9 | Â | 20/80.0 | 38/33.3 | Â |
HER2 | Â | Â | Â | Â | Â | Â |
Positive | 9/19.6 | 16/17.2 | 0.733a | 5/20.0 | 29/25.4 | 0.567a |
Negative | 37/80.4 | 77/82.8 | Â | 20/80.0 | 85/74.6 | Â |
Ki-67 (%) | Â | Â | Â | Â | Â | Â |
< 14 | 7/15.2 | 35/37.6 | 0.007a | 17/68.0 | 67/58.8 | 0.393a |
> 16 | 39/84.8 | 58/62.4 | Â | 8/32.0 | 47/41.2 | Â |
Subtypes | Â | Â | Â | Â | Â | Â |
LUMA | 9/19.6 | 28/30.1 | 0.628a, ^ | 4/16.0 | 33/28.9 | 0.010c, ^ |
LUMB (HER2-NEG) | 17/37.0 | 32/34.4 | Â | 7/28.0 | 42/36.8 | Â |
LUMB (HER2-POS) | 10/21.7 | 16/17.2 | Â | 4/16.0 | 22/19.3 | Â |
HER2 | 2/4.3 | 6/17.2 | Â | 1/4.0 | 7/6.1 | Â |
Basal-like | 6/13.0 | 4/4.3 | Â | 9/36.0 | 1/0.9 | Â |
UC | 2/4.3 | 7/7.5 | Â | 0/0 | 9/7.9 | Â |
Grade | Â | Â | Â | Â | Â | Â |
I | 0/0 | 0/0 | 0.921a, # | 0/0 | 0/0 | 0.001a, # |
II | 31/67.4 | 52/55.9 | Â | 10/40.0 | 73/64.0 | Â |
III | 12/26.1 | 21/22.6 | Â | 13/52.0 | 20/17.5 | Â |
UC | 3/6.5 | 20/21.5 | Â | 2/8.0 | 21/18.4 | Â |