Table 1 Patient and tumor characteristics (n = 210)
Factor | Â | Node-negative Node-positive | P value | |
|---|---|---|---|---|
| Â | # of sample | (n = 94) | (n = 116) | Â |
Age (yr) | 210 | 55.8 ± 12.4 | 51.7 ± 13.3 | 0.020 |
Age groups (yr) | Â | Â | Â | Â |
   ≤49 | 79 | 31 (33.0%) | 48 (41.4%) | 0.211 |
   ≥50 | 131 | 63 (67.0%) | 68 (58.6%) |  |
Tumor size (mm) | Â | Â | Â | Â |
   Tmicro | 3 | 3 (3.2%) | 0 | 0.001 |
   T1a | 6 | 3 (3.2%) | 3 (2.6%) |  |
   T1b | 23 | 13 (14.0%) | 10 (8.7%) |  |
   T1c | 54 | 33 (35.5%) | 21 (18.3%) |  |
   T2 | 99 | 37 (39.8%) | 62 (53.9%) |  |
   T3 | 13 | 4 (4.3%) | 9 (7.8%) |  |
   T4 | 10 | 0 | 10 (8.7% |  |
Histologic grade | Â | Â | Â | Â |
   1 | 43 | 19 (20.2%) | 24 (20.7%) | 0.091 |
   2 | 69 | 37 (39.4%) | 32 (27.6%) |  |
   3 | 86 | 31 (33.0%) | 55 (47.4%) |  |
   Unknown | 12 | 7 (7.4%) | 5 (4.3%) |  |
Lymphovascular invasion | Â | Â | Â | Â |
   Negative | 100 | 75 (79.8%) | 25 (21.6%) | <0.001 |
   Positive | 105 | 16 (17.0%) | 89 (76.7%) |  |
   Unknown | 5 | 3 (3.2%) | 2 (1.7%) |  |
Perineural invasion | Â | Â | Â | Â |
   Negative | 133 | 69 (73.4%) | 64 (55.2%) | 0.003 |
   Positive | 72 | 22 (23.4%) | 50 (43.1%) |  |
   Unknown | 5 | 3 (3.2%) | 2 (1.7%) |  |
Multicentricity | Â | Â | Â | Â |
   Negative | 153 | 75 (79.8%) | 78 (67.2%) | 0.300 |
   Positive | 56 | 18 (19.1%) | 38 (32.8%) |  |
   Unknown | 1 | 1 (1.1%) | 0 |  |
In situ carcinoma | Â | Â | Â | Â |
   Negative | 46 | 29 (30.9%) | 17 (14.7%) | 0.005 |
   Positive | 159 | 63 (67.0%) | 96 (82.8%) |  |
   Unknown | 5 | 2 (2.1%) | 3 (2.5%) |  |
Microcalcification | Â | Â | Â | Â |
   Negative | 136 | 66 (70.2%) | 70 (60.3%) | 0.087 |
   Positive | 67 | 24 (25.5%) | 43 (37.1%) |  |
   Unknown | 7 | 4 (4.3%) | 3 (2.6%) |  |
Epithelial hyperplasia | Â | Â | Â | Â |
   Negative | 104 | 57 (60.6%) | 47 (40.5%) | 0.002 |
   Positive | 96 | 32 (34.0%) | 64 (55.2%) |  |
   Unknown | 10 | 5 (5.4%) | 5 (4.3%) |  |