Figure 3From: Pulmonary epithelioid hemangioendothelioma accompanied by bilateral multiple calcified nodules in lungHistologic findings of the solitary mass. (A) At the periphery, tumor exhibited micropolypoid growth, and central coagulative necrosis existed in the cell cluster (H and E; original magnification ×100). (B) Several tumor cells showed marked cytologic atypia with large hyperchromatic nuclei, vesicular chromatin and prominent eosinophilic nucleoli (H and E; original magnification ×400). (C) The tumor showed extensive necrosis (upper) and invaded to bronchial mucosa and blood vessel (H and E; original magnification ×40). (D) Immunostaining for CD34 revealed strong and diffuse positivity of epithelioid cells and prominent cytoplasmic vacuoles and lumens (original magnification ×400).Back to article page