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Table 1 Summary of patient characteristics

From: Pulmonary tumor thrombotic microangiopathy induced by gastric carcinoma: Morphometric and immunohistochemical analysis of six autopsy cases

Case Age Sex Maximum diameter of tumor (mm) Macroscopic subtype Histopathological subtype Lymph-vascular involvement Metastasis Pulmonary arterial pressure
1 76 Male 70 Borrmann 3 por ly-3 v-2 Lung, diaphragm, pleura, peritoneum, liver, gallbladder, pancreas, adrenal gland, lymph nodes. 90 mmHg
2 82 Female 20 Borrmann 2 por ly-3 v-1 Lung, liver, pancreas, lymph nodes 10 mmHg
3 67 Female 30 Superficial depressed type por ly-3 v-1 Lung, esophagus, thyroid, pericardium, ovary, lymph nodes Unknown
4 67 Female 75 Borrmann 3 por ly-3 v-1 Esophagus, duodenum, ileum, jejunum, colon, mesenterium, liver, gallbladder, pancreas, kidney, adrenal gland, aorta, lymph nodes Unknown
5 49 Female 60 Borrmann 3 pap ly-3 v-2 Esophagus, duodenum, liver, pancreas, kidney, adrenal gland, lymph nodes Unknown
6 72 Male 20 Borrmann 2 por ly-3 v-1 Pancreas, spleen, kidney, adrenal gland, colon, spinal cord, lymph nodes Unknown
  1. por: poorly differentiated adenocarcinoma, pap: papillary adenocarcinoma, ly/v-1: minimal lympho-vascular involvement, ly/v-2: moderate lympho-vascular involvement, ly/v-3: prominent lympho-vascular involvement
  2. Patient age ranged from 49 to 82 years (mean ± standard deviation: 68.3 ± 11.3). The gender ratio was 4:2 (male to female). Maximum diameter of the tumor ranged from 20 to 70 mm (mean ± standard deviation: 45.8 ± 25.4). Main histology of gastric carcinoma involved poorly differentiated adenocarcinoma in five of the six cases (Case 1, 2, 3, 4, and 6), while the remaining case involved papillary adenocarcinoma (Case 5). Although all cases more or less showed lymph-vascular involvement, lymphatic involvement was prominent. Case 1 and 2 involved clinically proven and denied pulmonary hypertension, respectively.