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Table 3 Association of the level of promoter methylation with clinicopathologic charactristics of NSCLC

From: Association of promoter methylation with histologic type and pleural indentation in non-small cell lung cancer (NSCLC)

Genes Gender (n = 96) Histologic type (n = 96) Smoking history (n = 96)
  Female Male P SCC ADC P Y N P
  (n = 30) (n = 66)   (n = 66) (n = 30)   (n = 66) (n = 30)  
CALCA 145.0 ± 149.6 112.1 ± 106.5 0.28 152.1 ± 152.1 96.4 ± 90.6 0.07 155.2 ± 150.2 89.6 ± 92.7 0.03*
CDH1 33.1 ± 18.7 31.5 ± 21.2 0.71 35.4 ± 19.2 26.3 ± 18.6 0.03* 32.2 ± 18.7 33.4 ± 21.3 0.77
DAPK1 18.5 ± 59.6 23 ± 45.2 0.71 26.2 ± 65.8 5.9 ± 7.6 0.09 17.4 ± 59.6 25.4 ± 45.2 0.52
IRX2 96.4 ± 131.5 63.9 ± 34.8 0.19 92.3 ± 115.7 72.9 ± 103.6 0.43 95.3 ± 132.1 66.3 ± 36.1 0.24
TIMP3 60.5 ± 72.8 50.9 ± 39.1 0.50 64.9 ± 71.7 41.3 ± 39.8 0.09 61.5 ± 72.8 48.8 ± 38.9 0.37
PAX6 23.4 ± 15.1 24.2 ± 13.8 0.78 24.0 ± 15.5 23.1 ± 12.8 0.79 23.9 ± 15.6 23.3 ± 12.6 0.85
Genes Lymph node metastasis (n = 96) Pleural indentation (n = 96) Invasion or Adhesion (n = 96)
  Y N P Y N P Y N P
  (n = 26) (n = 70)   (n = 21) (n = 75)   (n = 31) (n = 65)  
CALCA 175.7 ± 175.1 119.5 ± 119.1 0.08 129.9 ± 132.5 136 ± 140.2 0.86 174.5 ± 160 115.1 ± 122.5 0.048*
CDH1 31.0 ± 13.9 33.1 ± 21.2 0.64 35.3 ± 21.2 31.8 ± 18.9 0.47 30.7 ± 16.6 33.5 ± 20.7 0.52
DAPK1 40.3 ± 100.5 12.3 ± 18.5 0.03* 12.4 ± 11.9 21.9 ± 62.3 0.49 10.9 ± 10.6 24.2 ± 66.6 0.27
IRX2 42.7 ± 51 91.2 ± 127.2 0.47 73.1 ± 38.4 89.9 ± 124.9 0.54 71.8 ± 48.3 93.1 ± 131.6 0.38
TIMP3 69.3 ± 91 53.2 ± 51 0.28 53.9 ± 42.9 58.6 ± 69.2 0.77 52.7 ± 53.1 59.8 ± 69.1 0.61
PAX6 23.2 ± 14.2 23.9 ± 14.9 0.83 25.2 ± 13.9 23.3 ± 14.9 0.59 25.8 ± 15.7 22.7 ± 14.1 0.32