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Table 1 Immunohistochemical reagents and results

From: Coexistence of early microinvasive endometrioid adenocarcinoma and CIN3 in the uterine cervix in a 32-year-old Japanese woman

    Results
Antigens Antibodies (clone) Sources EMEA. CIN3
Pancytokeratin AE1/3 Dako Corp. Glostrup, Denmark +++ +++
Pancytokeratin CAM5.2 Beckton-Dickinson, CA, USA ++ +
HMWCK 34βE12 Dako + +++
CK5/6 D5/16 Dako + +++
CK7 N1626 Dako + +
CK8 DC10 Dako - -
CK14 LL002 Novocastra, Newcastle upon type, UK - -
CK 18 DC10 Dako +++ -
CK 19 RCK 108 Progen, Heidelberg, Germany ++ -
CK 20 K20.8 Dako - -
EMA E29 Dako - +
Vimentin Vim 3B4 Dako - -
CEA polyclonal Dako - -
CA19-9 NS19-9 TBF Lab, Tokyo Japan + +
CA125 NS125 TFB Lab +++ +
Desmin D33 Dako - -
ASMA 1A4 Dako - -
p53 protein DO-7 Dako + +
p63 4A4 Dako - +++
Chromogranin DAK-A3 Dako - -
Synaptophysin Polyconal Dako - -
CD56 UJ13A Dako - -
CD68 KP-1 Dako - -
ER M7047 Dako +++ +++
PgR 1A6 Novocastra +++ -
HER2/neu CB11 Ventana Japan, Tokyo - -
MUC1 Ma695 Novocastra - +
MUC2 CCp58 Novocastra - -
MUC5AC CLH2 Novocastra - -
MUC6 CLH5 Novocastra - -
  1. +++, strongly positive. ++, moderately positive. +, mildly positive. -, negative. EMEA, early microinvasive endometrioid adenocarcinoma. CIN3, cervical intraepithelial neoplasm grade 3. HMWCK, high molecular weight cytokeratin. CK, cytokeratin. EMA, epithelial membrane antigen. CEA, carcinoembryonic antigen. CA19-9, carbohydrate antigen 19-9. CA125, carbohydrate antigen 125. ASMA, α-smooth muscle antigen. ER, estrogen receptor. PgR, progesterone receptor.
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Diagnostic Pathology

ISSN: 1746-1596

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