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Figure 1 | Diagnostic Pathology

Figure 1

From: Multifocal gastric gastrointestinal stromal tumors (GISTs) with lymph node metastases in children and young adults: A comparative clinical and histomorphological study of three cases including a new case of Carney triad

Figure 1

The primary tumor of the CT-GIST (case 1) showed a biphasic histomorphological growth pattern with spindled and epithelioid cells (a, H&E staining). Immunohistochemistry revealed an intensive predominantly membranous staining with C-KIT (b) and CD34 (d). The liver metastases revealed small nests and "Zellballen" of tumor cells with epithelioid growth pattern (c, H&E staining). The paraganglioma showed a characteristic nested pattern (e, H&E staining). Note similarity to hepatic metastasis from GIST in c.

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