Table 2 Peripheral hemogram and bone marrow variables in the studied groups
From: The prognostic value of p53 mutation in pediatric marrow hypoplasia
Variables | (FA) patients (n = 10) | (AAA) patients (n = 10) | (ITP)Control (n = 20) |
|---|---|---|---|
Peripheral blood (mean ± S.D) | 2.4 ± 0.6 ** | 3.3 ± 0.45 ** | 8.05 ± 0.85 |
- TLC (× 109/L) | 8.4 ± 0.9 * | 9.1 ± 0.5 * | 11.3 ± 0.55 |
- Hb (g/dl) | 102.4 ± 6.3 ** | 79.4 ± 3.5 | 83.3 ± 7.8 |
-MCV fl | 46.1 ± 8.4 ** | 110.5 ± 12.0 | 10.7 ± 2.1 ** |
- Platelets (× 109/L) |  |  |  |
BMA | Hypocellular | Hypocellular | Increase megakar -yocytes |
BMB | Â | Â | Not done |
Cellularity (no, %) | Â | Â | Â |
- Hypocellular (grades 1, 2, 3) | 8/10 (80%) | 6/10 (60%) | - |
- Normal (grade 4) | 2/10 (20%) | 1/10(10%) | - |
- Hypercellular (grades 5, 6) | - | - | - |
Fibrosis | - | 3/10 (30%) | - |