From: Decreased D2-40 and increased p16INK4A immunoreactivities correlate with higher grade of cervical intraepithelial neoplasia
D2-40 expression (%)
Lesion type
n
negative
focal
diffuse
Positivity
Normal cervix
21
0 (0)
21 (100%)
100%
CIN 1
32
1(2.8%)
31 (97.2%)
CIN 2
37
20 (54.1%)
16 (43.2%)
1 (2.7%)
45.9%
CIN 3
35
22 (62.8%)
12 (34.3%)
1 (2.9%)
37.1%