Histological examination. (A)The tumor is nodular and different nodules are separated by collagen fibers. Different nodules show different histologic features (H&E × 40). (B) Pleomorphic cellular infiltrate containing lymphocytes, eosinophils, neutrophils and large Reed-Sternberg cells (arrows) (H&E × 400). (C) Other nodules display sheets of relatively uniform large lymphoid cells with typical morphologic features of large cell lymphoma (H&E × 100).