Lobular neoplasia: frequency and association with other breast lesions

Diagnostic Pathology

Table 2 Frequency of association between subtypes of lobular neoplasia and columnar cell lesions (CCL)

CCL	ALH		DIALH		LCIS		LCIS pleo		Total
	n	%	n	%	n	%	n	%	n	%
CCC	14	22.6	13	21.0	15	24.2	0	0	42	67.7
CCH	4	6.5	3	4.8	2	3.2	0	0	9	14.5
CCC with atypia	1	1.6	3	4.8	4	6.5	1	1.6	9	14.5
CCH with atypia	0	0	0	0.0	1	1.6	1	1.6	2	3.2
Total	19	30.6	19	30.6	22	35.5	2	3.2	62	100.0

ALH = atypical lobular hyperplasia; DIALH = ductal involvement by cells of atypical lobular hyperplasia; LCIS = lobular carcinoma in situ; LCIS pleo = LCIS pleomorphic; CCC = columnar cell change; CCH = columnar cell hyperplasia; CCC with atypia = columnar cell change with atypia; CCH with atypia = columnar cell hyperplasia with atypia; n = number of cases. χ² test for trend: p = 0.03.

ISSN: 1746-1596