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Table 4 Summary of immunohistochemical results of the 22 cases of extranodal NK/T-cell lymphoma, nasal type

From: Aberrant antigenic expression in extranodal NK/T-cell lymphoma: a multi-parameter study from Thailand

Marker Total cases Mostly positive Partially positive Overall positivity Probably negative Clearly negative Overall negativity
CD3 22 15 (68%) 5 (23%) 20 (91%) 0 2 (9%) 2 (9%)
CD20 22 0 0 0 0 22 (100%) 22 (100%)
CD5 22 0 2 (9%) 2 (9%) 0 20 (91%) 20 (91%)
CD7 19 5 (26%) 1 (5%) 6 (32%) 1 (5%) 12 (63%) 13 (68%)
CD4 22 0 3 (14%) 3 (14%) 0 19 (86%) 19 (86%)
CD8 22 0 0 0 0 22 (100%) 22 (100%)
βF1 22 0 0 0 0 22 (100%) 22 (100%)
CD56 22 15 (68%) 3 (14%) 18 (82%) 1 (5%) 3 (14%) 4 (18%)
CD57 21 0 0 0 0 21 (100%) 21 (100%)
TIA-1 22 22 (100%) 0 22 (100%) 0 0 0
Granzyme B 22 13 (59%) 8 (36%) 21 (95%) 1 (5%) 0 1 (5%)
Perforin 22 14 (64%) 5 (23%) 19 (86%) 2 (9%) 1 (5%) 3 (14%)
CD45 18 8 (44%) 7 (39%) 15 (83%) 0 3 (17%) 3 (17%)
CD43 22 20 (91%) 2 (9%) 22 (100%) 0 0 0
CD30 20 10 (50%) 5 (25%) 15 (75%) 0 5 (25%) 5 (25%)
ALK 18 0 0 0 0 18 (100%) 18 (100%)
OCT2 20 1 (5%) 4 (20%) 5 (25%) 3 (15%) 12 (60%) 15 (75%)
IRF4/MUM1 15 1 (7%) 4 (27%) 5 (33%) 0 10 (67%) 10 (67%)
  1. Mostly positive = definitely positive on lymphoma cells >50%
  2. Partially positive = 10-50% positive staining
  3. Overall positive = sum of mostly and partially positive results
  4. Probably negative = <10% staining on presumptive lymphoma cells
  5. Clearly negative = clearly negative
  6. Overall negative = sum of probably negative and clearly negative results