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Table 1 Concordance of HER2 immunohistochemistry visual evaluation and digital analysis by each tissue microarray spot

From: Membrane connectivity estimated by digital image analysis of HER2 immunohistochemistry is concordant with visual scoring and fluorescence in situ hybridization results: algorithm evaluation on breast cancer tissue microarrays

VE1 HER2 score VE2 HER2 score
  0/1+ 2+ 3+ Total
0/1+ 475 15 0 490
2+ 0 21 4 25
3+ 0 4 56 60
VE1 HER2 score DA HER2 score
  0/1+ 2+ 3+ Total
0/1+ 458 32 0 490
2+ 4 18 3 25
3+ 0 0 60 60
VE2 HER2 score DA HER2 score
  0/1+ 2+ 3+ Total
0/1+ 454 21 0 475
2+ 8 26 6 40
3+ 0 3 57 60
  1. The concordance per spot is based on individual TMA spot HER2 score value: VE1 and VE2 - first and second visual evaluation by the pathologist; DA - digital analysis score.