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Table 1 Concordance of HER2 immunohistochemistry visual evaluation and digital analysis by each tissue microarray spot

From: Membrane connectivity estimated by digital image analysis of HER2 immunohistochemistry is concordant with visual scoring and fluorescence in situ hybridization results: algorithm evaluation on breast cancer tissue microarrays

VE1 HER2 score

VE2 HER2 score

 

0/1+

2+

3+

Total

0/1+

475

15

0

490

2+

0

21

4

25

3+

0

4

56

60

VE1 HER2 score

DA HER2 score

 

0/1+

2+

3+

Total

0/1+

458

32

0

490

2+

4

18

3

25

3+

0

0

60

60

VE2 HER2 score

DA HER2 score

 

0/1+

2+

3+

Total

0/1+

454

21

0

475

2+

8

26

6

40

3+

0

3

57

60

  1. The concordance per spot is based on individual TMA spot HER2 score value: VE1 and VE2 - first and second visual evaluation by the pathologist; DA - digital analysis score.