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Table 2 Patients' HER2 immunohistochemistry score in the TMAs represented by a range and maximum spot value

From: Membrane connectivity estimated by digital image analysis of HER2 immunohistochemistry is concordant with visual scoring and fluorescence in situ hybridization results: algorithm evaluation on breast cancer tissue microarrays

VE1range

VE1max

 

0/1+

2+

3+

Total

0

136

4

16

156

1

0*

4

0

4

2

0*

0*

1

1

VE2range

VE2max

 

0/1+

2+

3+

Total

0

129

6

16

151

1

0*

9

1

10

2

0

0*

0

0

DArange

DAmax

 

1

2

3

Total

0

122

3

16

141

1

0*

16

3

19

2

0*

0*

1

1

  1. * the range cannot logically be 1 or 2.
  2. The cross tabulation of the patients' HER2 score range and maximum values represents variation of the analysis results between individual patient's spots. VE1max and VE2max - first and second visual evaluation by the pathologist, DAmax - digital analysis score. Accordingly, VE1range, VE2range, and DArange represent range between a minimum and maximum spot HER2 score value.
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Diagnostic Pathology

ISSN: 1746-1596

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