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Table 2 Patients' HER2 immunohistochemistry score in the TMAs represented by a range and maximum spot value

From: Membrane connectivity estimated by digital image analysis of HER2 immunohistochemistry is concordant with visual scoring and fluorescence in situ hybridization results: algorithm evaluation on breast cancer tissue microarrays

VE1range VE1max
  0/1+ 2+ 3+ Total
0 136 4 16 156
1 0* 4 0 4
2 0* 0* 1 1
VE2range VE2max
  0/1+ 2+ 3+ Total
0 129 6 16 151
1 0* 9 1 10
2 0 0* 0 0
DArange DAmax
  1 2 3 Total
0 122 3 16 141
1 0* 16 3 19
2 0* 0* 1 1
  1. * the range cannot logically be 1 or 2.
  2. The cross tabulation of the patients' HER2 score range and maximum values represents variation of the analysis results between individual patient's spots. VE1max and VE2max - first and second visual evaluation by the pathologist, DAmax - digital analysis score. Accordingly, VE1range, VE2range, and DArange represent range between a minimum and maximum spot HER2 score value.