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Table 4 Proportion of HER2 FISH-positive cases in the IHC score categories by visual evaluation and digital analysis

From: Membrane connectivity estimated by digital image analysis of HER2 immunohistochemistry is concordant with visual scoring and fluorescence in situ hybridization results: algorithm evaluation on breast cancer tissue microarrays

 

HER2 FISH positive (%)

HER2 score

VE1max

VE2max

DAmax

0/+1

8/127 (6.3)

7/120 (5.8)

5/113 (4.4)

2+

2/8 (25.0)

2/15 (13.3)

3/19 (15.8)

3+

14/17 (82.4)

15/17 (88.2)

16/20 (80.0)

Total

152

152

152

  1. Number and percentage (in parentheses) of FISH-positive patients in the IHC score categories by maximum TMA spot HER2 score value: VE1max and VE2max - first and second visual evaluation by the pathologist, DAmax - digital analysis score.
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Diagnostic Pathology

ISSN: 1746-1596

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