Table 1 Clinical, histological, phenotypical and molecular findings in the series of 82 FL
Gender | F | 46 |
| Â | M | 36 |
Age | Median 58 | Range 20-88 |
Type of FL | Nodal FL | 67 |
| Â | Combined FL+DLBCL | 10 |
| Â | Cutaneous | 5 |
Pattern | "In situ neoplasia" | 6 (7.8%) |
| Â | Nodular | 62 (80.5%) |
| Â | Nodular and diffuse | 5 (6.5%) |
| Â | Diffuse | 4 (5.2%) |
WHO Grade | Grade 1 | 8 (11.3%) |
| Â | Grade 2 | 37 (52.1%) |
| Â | Grade 3 | 26 (36.6%) |
Marginal differentiation | Yes | 7 (9.9%) |
| Â | No | 64 (90.1%) |
BCL6 | Positive | 76 (92.7%) |
| Â | Negative | 6 (7.3%) |
CD10 | Positive | 74 (90.2%) |
| Â | Negative | 8 (9.8%) |
BCL2 | Positive | 72 (87.8%) |
| Â | Negative | 10 (12.2%) |
Ki67 antigen | Low | 23 |
| Â | Intermediate | 30 |
| Â | High | 29 |
IGH gene rearrangement | Monoclonal | 66 (80.5%) |
| Â | Polyclonal | 16 (19.5%) |
MBR-BCL2/JH rearrangement | Present | 19 (23.2%)/15 (27.3%)* |
| Â | Absent | 63 (76.8%)/40 (72.7%)* |