Prognosis of ampullary cancer based on immunohistochemical type and expression of osteopontin

Diagnostic Pathology

Table 2 Expression of OPN and survival time of patients with different subtypes of ampullary carcinoma (AC).

Survival time in months (number of patients)
	Pancreatobiliary	Intestinal	Other	p value¹
Total	23 ± 4.2 (24)	38 ± 2.8 (29)	64 ± 16.8 (67)	0.052
OPN^-	69 ± 39.5 (11)	41 ± 24.8 (16)	69 ± 26.8 (37)	0.750
OPN⁺	22 ± 6.6 (13)*	37 ± 1.4 (13)	36 ± 0.9 (30)	0.017
p value²	0.085	0.509	0.263

Survival time is expressed as median ± SD. ¹p-value for comparison of the 3 types; ²p-value for comparison of the OPN⁺ and OPN^- groups. * p = 0.041 and p = 0.010 for comparison with the intestinal type and other type OPN⁺ AC, respectively. There was no difference between intestinal AC and other type of AC (p = 0.907).

ISSN: 1746-1596