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Table 1 Digital slide scanners in Pathology

From: COST Action “EuroTelepath”: digital pathology integration in electronic health record, including primary care centres

System

Vendor

Objective/NA

# slides

Light path

File format

ACIS® III

Dako http://www.dako.com/

Nikon 4x, 10x, 20x, 40x, 60x

100

Halogen lamp

JPEG, TIFF, BMP

Applied Imaging Ariol®

Genetix http://www.genetix.com/

Motorized microscope. 1.25x, 5x, 10x, 20x (0.36 μm/pixel), 40x (0.18 μm/pixel)

50

Fluorescence available

JPEG

dotSlide™

Olympus http://www.olympus.co.uk/microscopy/22.htm

Motorized microscope. 2x plapon, 10x, 20x, 40x uplsapo

1 (50)

Halogen lamp. Fluorescence, polarisation available

Olympus VSI , JPEG, TIFF , JPEG2000

GoodSpeed®

Alphelys http://www.alphelys.com/

Motorized microscope

4 or 8

Dark field and fluorescence available

JPEG

iSan 2.0™

BioImagene http://www.bioimagene.com/

Olympus 20x/0.50 (0.46um/pixel) Plan Fluor

Olypus 40x/0.75 (0.23um/pixel) Plan Fluor

160

Bright-field, integrated LED

JPEG2000, BIF, TIFF

iScan Coreo Au™

BioImagene http://www.bioimagene.com/

Automated turret with 4 objectives: Olympus 4X (0.1 NA), 10X (0.3 NA), 20X (0.5 NA), and 40X (0.75 NA)

160

Bright-field, integrated LED

JPEG2000, BIF, TIFF

iScan Concerto™

BioImagene http://www.bioimagene.com/

Automated turret with 4 objectives: Olympus 4X (0.13 NA), 10X (0.3 NA), 20X (0.5 NA), and 40X (0.75 NA) or 60X (0.90NA, 0.15 μm/pixel)

80

Integrated LED. Fluorescence available

JPEG2000, BIF, TIFF

Pannoramic Desk®

3DHistech http://www.3dhistech.com/

20x/0.80 (0.23 μm) Plan Apo.

40x/0.95 Plan Apo

1

Bright-field, halogen lamp

Mirax format, JPEG, TIFF

Pannoramic Midi®

3DHistech http://www.3dhistech.com/

20x/0.80 (0.23 μm) Plan Apo.

40x/0.95 Plan Apo

12

Fluorescence available

Mirax format, JPEG, TIFF

Pannoramic Scan®

3DHistech http://www.3dhistech.com/

20x/0.80 (0.23 μm) Plan Apo.

40x/0.95 Plan Apo

150

Fluorescence available

Mirax format, JPEG, TIFF

Pannoramic 250®

3DHistech http://www.3dhistech.com/

20x/0.80 (0.23 μm) Plan Apo.

40x/0.95 Plan Apo

250

Fluorescence available

Mirax format, JPEG, TIFF

NanoZoomer® HT

Hamamatsu http://www.hamamatsu.com/

20x/0.7. Modes:

x20 (0.46 µm/pixel)

x40 (0.23 µm/pixel)

210

Fluorescence available

JPEG, TIFF

NanoZoomer® RS

Hamamatsu http://www.hamamatsu.com/

20x/0.75. Modes:

x10 (0.92 µm/pixel)

x20 (0.46 µm/pixel)

x40 (0.23 µm/pixel)

6

Fluorescence available

JPEG, TIFF

Nuance FX

CRi http://www.cri-inc.com/

Spectral range 420 – 720 nm

1

Bright field and fluorescence multispectral imaging

.im3 for multispectral; 24-bit TIFF for RGB

ScanScope® CS

Aperio http://www.aperio.com/

20x/0.75 Plan Apo

5

Bright-field, halogen lamp

TIFF (Aperio SVS), CWS

ScanScope® GL

Aperio http://www.aperio.com/

20x/0.75 Plan Apo

1

Bright-field, halogen lamp

TIFF (Aperio SVS), CWS

ScanScope® GL-E

Aperio http://www.aperio.com/

20x/0.75 Plan Apo

1

Bright-field, halogen lamp

Composite WebSlide (CWS)

ScanScope® OS

Aperio http://www.aperio.com/

60x/1.35 Plan Apo

1

Oil immersion

TIFF (Aperio SVS), CWS

ScanScope® XT

Aperio http://www.aperio.com/

20x/0.75 Plan Apo

120

Bright-field, halogen lamp

TIFF (Aperio SVS), CWS

Toco™

Claro http://www.claro-inc.jp/

Carl Zeiss Aplan

20x, 40x

1

Bright-field, flat LED

Claro format, JPEG

Vassalo™

Claro http://www.claro-inc.jp/

Carl Zeiss Aplan

20x,40x

80 or 20

Bright-field, flat LED

Claro format, JPEG