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Table 3 Correlation between hepatitis C virus quantitation in serum and protein Kinase R in liver tissue

From: Implication of protein kinase R Gene quantification in hepatitis C Virus Genotype 4 induced Hepatocarcinogenesis

 

Serum viral load

PKR gene expression in liver

GII

(HCV-4)

GIII

(HCV-4 related HCC)

Spearman's correlation coefficient (rs)

−0.56

−0.46

P-value

0.004

0.02

  1. A significant negative correlation is shown between both studied groups, in which lower serum viral load was associated with higher PKR gene expression
  2. GII (HCV-4): group II with hepatitis C virus genotype 4; GIII (HCV-4 related HCC): group III with hepatitis C virus genotype 4 related hepatocellular carcinoma; PKR: protein kinase R.
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Diagnostic Pathology

ISSN: 1746-1596

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