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Table 4 Correlation between grading and staging of chronic hepatitis and protein kinase R in liver tissue

From: Implication of protein kinase R Gene quantification in hepatitis C Virus Genotype 4 induced Hepatocarcinogenesis

  PKR gene expression in liver
GII (HCV-4) GIII (HCV-4 related HCC)
Spearman's correlation coefficient r s P-value r s P-value
HAI 0.83 0.0001 0.89 0.0001
Fibrosis o.56 0.004 0.84 0.0001
  1. A significant positive correlation is obvious in which higher HAI and fibrosis scores are associated with high rate of PKR gene expression.
  2. GII (HCV-4): group II with hepatitis C virus genotype 4; GIII (HCV-4 related HCC): group III with hepatitis C virus genotype 4 related hepatocellular carcinoma; HAI: histological activity.
  3. Index; PKR: protein kinase R.